磷酸化蛋白激酶樣內(nèi)質(zhì)網(wǎng)激酶抗體

Name: 磷酸化蛋白激酶樣內(nèi)質(zhì)網(wǎng)激酶抗體bs-23340R
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簡(jiǎn)要描述：The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010].